The Low Pressure Test Bed (LPTB) is a recently developed hypobaric (low atmospheric pressure) chamber that has some unique capabilities not found in normal hypobaric chambers. The LPTB chamber not only controls atmospheric pressure but also temperature, relative humidity, and air speed. The chamber is also designed for inserts that give the capability of maintaining and measuring low level Volatile Organic Compounds (VOCs). The chamber itself can accommodate different gas mixtures to simulate different atmospheres. The chamber is located in the Controlled Environment Laboratory (CEL) at Kennedy Space Center’s Space Life Sciences Laboratory (SLSL). The laboratory maintains a centralized Command, Monitoring and Data System (CMDS) for logging and storing data collected from experiments or tests done in the LPTB. It is used to support projects related to NASA ESMD, SMD, CEV, and SOMA needs, as well as external industrial and academic users. This chamber is ideally suited for testing of sensors and equipment at reduced pressures.